ANM
2010
3rd
International Conference on Advanced Nano
Materials
12-15 September 2010 - Agadir, Morocco
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Abstract
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ANMM110 |
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LINKING MECHANICS TO BIOCHEMISTRY IN
MOLECULAR AND CELLULAR BEHAVIOR THROUGH NANO- AND MICRO-TECHNOLOGY AND
BIOLOGICAL INSPIRED NANOTECHNOLOGY |
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Philip LeDuc |
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Departments of Mechanical and
Biomedical Engineering, Lane Center for Computational Biology and
Biological Sciences, Carnegie Mellon University, USA |
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The
link
between mechanics and biochemistry has been implicated in a myriad of
scientific and medical problems, from orthopaedics and cardiovascular
medicine,
to cell motility and division, to signal transduction and gene
expression. Most of these studies have
been focused on
organ-level issues, yet cellular and molecular research has become
essential
over the last decade in this field thanks to the revolutionary
developments in
microelectronics, genetics, biotechnology, and information technology.
Here, I
will present some of our latest work with nano- and micro- technology
developments that are being patented and how they are being used to
probe
scientific questions related to cellular and molecular structure. I
will
illustrate why the link between mechanics and biochemistry matters to
biology
and medicine with respect to the structural regulation and
control-feedback
approaches in living cells. Also, I will talk about novel approaches to
nanotechnology
development through focusing on nature inspired design principles at
the
molecular and cellular levels. Furthermore, by combining novel
approaches
through engineering and technology, these multidisciplinary ideas can
make a
significant impact to the studies on human health and diseases as well
as have
applications in entrepreneurial enterprises. |
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