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   ANM 2010
    3rd International Conference on Advanced Nano Materials
    12-15 September 2010 - Agadir, Morocco

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   Abstract


ANMM110
LINKING MECHANICS TO BIOCHEMISTRY IN MOLECULAR AND CELLULAR BEHAVIOR THROUGH NANO- AND MICRO-TECHNOLOGY AND BIOLOGICAL INSPIRED NANOTECHNOLOGY
Philip LeDuc
Departments of Mechanical and Biomedical Engineering, Lane Center for Computational Biology and Biological Sciences, Carnegie Mellon University, USA
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The link between mechanics and biochemistry has been implicated in a myriad of scientific and medical problems, from orthopaedics and cardiovascular medicine, to cell motility and division, to signal transduction and gene expression.  Most of these studies have been focused on organ-level issues, yet cellular and molecular research has become essential over the last decade in this field thanks to the revolutionary developments in microelectronics, genetics, biotechnology, and information technology. Here, I will present some of our latest work with nano- and micro- technology developments that are being patented and how they are being used to probe scientific questions related to cellular and molecular structure. I will illustrate why the link between mechanics and biochemistry matters to biology and medicine with respect to the structural regulation and control-feedback approaches in living cells. Also, I will talk about novel approaches to nanotechnology development through focusing on nature inspired design principles at the molecular and cellular levels. Furthermore, by combining novel approaches through engineering and technology, these multidisciplinary ideas can make a significant impact to the studies on human health and diseases as well as have applications in entrepreneurial enterprises.
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